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diagnosis hematology algorithm causes workup hemolytic management oncology classification pancytopenia chronic cold deficiency erythematosus extravascular intravascular lupus macrocytic monoclonal nutrition
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... and hemolysis: ... #Anemias #Differential ... Diagnosis #Algorithm #hematology
Algorithm for the Diagnosis and Workup of Hemolytic Anemia By Dr. Kylie Adamek @KylieAdamek #Hemolytic #Anemia #Algorithm #Differential
the Diagnosis and ... Anemia By Dr ... #Anemia #Algorithm ... #Differential # ... Diagnosis #Workup #Hematology
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Hemolytic Anemia ... Mechanism: IgG and ... Lymphoproliferative disorder ... , Autoimmune disorder ... #Anemia #hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Hemolytic #Anemia ... #Algorithm #Differential ... Causes #Workup #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Bleed • Hemolysis ... Inflammation • Cancer ... #Differential # ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... lymphoproliferative disorders ... disease, Copper and ... Extravascular #Causes #differential ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Extravascular and ... - Differential ... anemia • ... Extravascular #Differential ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... telomeropathy Cancer ... Inflammatory and ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider RBC membrane disorder ... #Anemia #Differential ... Algorithm #workup #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
infiltration (e.g. cancer ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
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