912 results
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
in mesolimbic projection ... in mesocortical projection ... decision-making, language production ... Schizophrenia #pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Expression → ↑ VLDL Production ... Secretion → ↑ LDL Production ... sequestration #pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Decreased tear production ... Decreased saliva production ... Decreased mucous production ... Decreased sebum production ... Sjogrens #Syndrome #Pathophysiology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... - inadequate production ... #dka #hhs #pathophysiology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Biliary Cirrhosis - Pathophysiology ... relative with PBC Pathophysiology ... - Loss of the protective ... Biliary #Cirrhosis #Pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Increased Cell Production ... potassium #low #pathophysiology
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... cancer • Ectopic production ... Hypercalcemia #Malignancy #Pathophysiology
Mechanism of Gastric HCL secretion and production

#gastric #acid #secretion #pathophysiology
secretion and production ... acid #secretion #pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Estrogen) • Inhibit production ... Osteoclasts • Inhibit production ... #Osteoporosis #pathophysiology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
sources of ammonia production ... into increased production ... asparaginase Excess (production ... deficiency #Ammonia #Pathophysiology