2826 results
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... SLE Hallmark = proteinuria ... therapy Goal: proteinuria ... Focal LN (<50% of glomeruli ... Diffuse LN (>50% of glomeruli
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
urinalysis, labs - Management ... INTRINSIC: - Glomerular ... red blood cells/proteinuria ... renal biopsy - Management ... ultrasonography - Manaqement
Renal Biopsy - Absolute and Relative Contraindications
WHEN NOT TO DO IT:
 • Isolated glomerular hematuria, unless
: • Isolated glomerular ... • Low grade proteinuria ... Contraindications #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
• Renal: (AKI, proteinuria ... casts, low grade proteinuria ... hypercellular glomeruli ... differential #diagnosis #management
Glomerular Diseases - Spectrum
 - Insidious vs Acute
 - Nephritic (hypertension, hematuria, renal failure) vs Nephrotic
Glomerular Diseases ... Nephrotic (Heavy proteinuria ... Mehr @poyanmehr #Glomerular
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... Proteinuria often ... Massive proteinuria ... diabetes)) #Glomerular ... Classification #Proteinuria
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Algorithm Persistent Proteinuria ... UTI Orthostatic Proteinuria ... • Drugs Glomerular ... Proteinuria (Positive
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria, proteinuria ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... monitoring low-level glomerular ... proteinuria. ... common causes of glomerular ... disorders #glomerular
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... the patient have glomerular