295 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
of Scleroderma (SSc ... dysmotility, SIBO, GAVE, pseudoobstruction ... renal crisis (SRC ... #Scleroderma #SSc
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SLE, SSc ... SjS, SLE, DM, SSc ... , PM/SSc OS, MCTD ... pattern: - SSc ... , PBC/SSc OS
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anti-Smith, Anti-Ro (SSA ... ) and Anti-La (SSB ... Syndrome: Anti-Ro (SSA ... ), Anti-La (SSB) ... Systemic Sclerosis, SSc
POCUS Echocardiography - Table of Cardiac Views and Windows
 • Parastemal Long-Axis View (PLAX)
 • Parasternal
• Subcostal (SC ... Inferior Vena Cava (SC ... View (A5C) • SC ... Suprasternal Notch (SSN ... View (A3C) • SSN
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
lupus (90%) Anti-SSA ... 30-40% Target: SS-A ... Sjogren Anti-SSB ... Associated with SLE-SSc-AlM
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
pattern: • SLE, SSc ... SjS, SLE, DM, SSc ... , PM/SSc OS, MCTD ... , PBC/SSc OS • ... , PM/SSc OS, Raynaud
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Sjogren's Syndrome (SS ... or scleroderma (SSc
Management of interstitial lung disease (ILD)-associated with systemic sclerosis (SSc)

Therapeutic indication: absolute decline in FVC >10%
systemic sclerosis (SSc ... systemicsclerosis #SSc
Echocardiogram Windows - Nomenclature
Each view is described using three (3) components
1) Transducer Position or "Window"
A: Apical SC ... Subcostal SSN
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-Sm - SLE Anti-SSA ... (Ro), Anti-SSB