11 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Arthralgias • Eye ... purpura: strong sign ... diminished, or tender pulses ... Eye -> retinopathy
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Weight loss (50%) Eye ... Butterfly rash, Vasculitis ... Endocarditis, Aortic ... erythematosus #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Arthralgias • Eye ... purpura: Strong sign ... < 30 years • Aorta ... or as primary condition ... tract, and often causes
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Extra-articular and Other Conditions ... Eyes • Iritis ... Lyme disease, Vasculitis ... Diminished peripheral pulses ... #diagnosis #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin condition ... autoinflammatory conditions ... Episcleritis Signs ... Causes: - Idiopathic ... Leukocytoclastic vasculitis
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Manifestations • Optic ... /pain upon eye movement ... Manifestations #diagnosis ... neurology #symptoms #signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... : Inflammatory eye ... inhibitors • Uveitis- Ophthalmology ... Nonsurgical abdominal pain ... #management #signs
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
- Differential Diagnosis ... meningeal irritation signs ... Disorder of the eyes ... headache • CNS Vasculitis ... #ophthalmology
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
Pathogenesis and clinical ... , CRP, WBC - Aortic ... Decr palpable pulses ... Takayasus #Arteritis #Vasculitis ... #Diagnosis #Signs
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... Diagnosis = clinical ... systemic sx + signs ... = vasculitis vs ... required +/- prompt ophthalmology