13 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... Arthralgias • Eye ... diminished, or tender pulses ... Eye -> retinopathy
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... signs #lesions #diagnosis ... #clinical #manifestations ... #pathology #lesions
Transient Monocular Vision loss - Differential Diagnosis
Ischemia	
 - Large artery disease (atherothrombosis, embolus, dissection).
  -
- Differential Diagnosis ... - Large artery disease ... neuropathy, vasculitis ... changes in gaze/eye ... #Ophthalmology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Arthralgias • Eye ... < 30 years • Aorta ... claudication, pulse ... Arteritis): • Aorta ... tract, and often causes
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Weight loss (50%) Eye ... Butterfly rash, Vasculitis ... Endocarditis, Aortic ... (20%) Renal disease
Salmonella Aspiration on Microscopy

66 y/o male with history of coronary artery disease presents with abdominal pain.
coronary artery disease ... with abdominal pain ... shows an abdominal aortic ... Diagnosis ? ... #pathology #microbiology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... : Inflammatory eye ... Genital ulcers • Eye ... inhibitors • Uveitis- Ophthalmology ... Nonsurgical abdominal pain
Blurry Vision - Differential Diagnosis Framework

Anatomical Approach to Eye Disease:
1. Lids/Lashes
2. Extraocular Muscles/Motility
3. Conjunctiva/Sclera
4. Cornea
5. Anterior
- Differential Diagnosis ... Disease: 1. ... pain (with or without ... #ophthalmology ... #causes
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Eyes • Iritis ... , Vasculitis (e.g ... Rheumatic fever • Aortic ... Diminished peripheral pulses ... #differential #diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Manifestations • Optic ... /pain upon eye movement ... involvement: Intractable nausea ... Manifestations #diagnosis