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diagnosis nephrology differential causes nephrotic hematuria nephritic rheumatology syndrome blood chronic ckd clinical comparison diseases electronmicroscopy glomerulonephritis kidneydisease lupus management
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... Proteinuria often ... Massive proteinuria ... diabetes)) #Glomerular ... Nephrotic #Syndromes #Classification
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria, proteinuria ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular ... Glomerulonephritis #RPGN #Classification
This image shows scanning EM of a proteinuric glomerulus with capillary loop showing widening and partial
scanning EM of a proteinuric ... glomerulus with ... interdigitating podocyte ... arkanalabs #glomerulus ... SEM #clinical #proteinuric
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 Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
hematuria and/or proteinuria ... the patient have glomerular ... Syndrome #Comparison #Algorithm
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... Persistent Proteinuria ... • Drugs Glomerular ... Differential #Diagnosis #Algorithm
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... presenting with overt glomerular ... Cytomegalovirus; GBM = glomerular ... #Algorithm #differential ... #diagnosis #glomerular
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... • Calculi Glomerular ... epithelial side of glomerular ... endothelial side of glomerular ... nephrotic range) proteinuria
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
SLE Hallmark = proteinuria ... therapy Goal: proteinuria ... by 12 months Classification ... Focal LN (<50% of glomeruli ... Diffuse LN (>50% of glomeruli
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... • Evidence of glomerular ... bleeding (proteinuria ... Hematuria #Diagnosis #Algorithm
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Differential Diagnosis Algorithm ... Atherosclerosis Glomerular ... (Proteinuria) ... Differential #Diagnosis #Algorithm
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