16 results
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 
1. Old samples
#Stomatocytes #Spherocytes ... #Schistocytes #Pyknocytes
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
Spherocytes - The ... to one of many spherocytes ...

Causes of spherocyte ... When spherocytes ... Spherocytes show

Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
red cell and a spherocyte ... membrane loss, and spherocyte ... Spherocytes are
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Thalassemia • Spherocytes ... spherocytosis Acquired: • Spherocytes
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
negative - Smear: spherocytes
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Sickle cell, Spherocyte
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
increase in: - spherocytes
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
for IgG +/- C3, Spherocytes
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
reticulocyte count • Spherocytes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Macrocytes, RBC Spherocytes