12 results
Reproductive Number (R0 "R Naught") showing how contagious / transmissible a pathogen is.  The R0
Reproductive Number (R0 ... The R0 for Wuhan ... Diphtheria R0 ... Fatality 2-3% ** 'Ro ... #Ro #RNaught #Contagious
Case Fatality Rate (CFR) and R0 of the Novel Coronavirus 2019 compared to other famous contagious
Rate (CFR) and R0 ... NCOV2019 #Wuhan #CFR #R0
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anti-Smith, Anti-Ro ... Syndrome: Anti-Ro
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
SLE Anti-SSA (Ro
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
activity Anti-Ro
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-Ro/SSA
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
lesions • Anti-Ro ... • Anti-Smith, Ro ... ANA + (+) anti-Ro
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
40% Target: SS-A/Ro
COVID-19 - A Seattle Intensivist's One-Page Cheat-Sheet on COVID-19 v2.7 Updated March 26 2020

(v2.7) incorporating newer
rate = 30-40% • Ro
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Serology: - Anti-Ro