31 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus (SLE ... Anti-Smith, Anti-Ro ... Syndrome: Anti-Ro ... #Rheumatology #diagnosis
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Anti-SSA (Ro), ... Associations #diseases #diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
activity Anti-Ro ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE ... #Summary #diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... 40% Target: SS-A/Ro ... higly specific for SLE ... erythematosus #diagnosis
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
additions, for diagnosing ... See IEM schema for ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #Neonatology #Peds ... Laboratory #Patterns #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
lesions • Anti-Ro ... Differential Diagnosis ... • Anti-Smith, Ro ... ANA + (+) anti-Ro ... Erythematosus #Diagnosis
This table, along with our detailed references can be found online at http://www.pedscases.com/pediatric-vital-signsreference-chart .
For a more
to this topic, see ... #Diagnosis #Peds
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
in drug-induced SLE ... Anti-Ro/SSA ... Antineutrophil #antibodies #diagnosis
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
See the lab values ... Pathophysiology #Diagnosis ... #Neonatology #Peds
Clinical Features and Complications of Measles

Rash:
Spreads downwards, from behind the ears to the whole Of the
but difficult to see ... #Measles #Diagnosis ... Kopliks KoplikSpots #Peds