50 results
Reproductive Number (R0 "R Naught") showing how contagious / transmissible a pathogen is.  The R0
The R0 for Wuhan ... , MERS, Ebola) and ... Fatality 2-3% ** 'Ro ... is preliminary and ... #Ro #RNaught #Contagious
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus ... (SLE): ANA (anti-nuclear ... Anti-Smith, Anti-Ro ... glycoprotein I (ß2GP), Lupus ... Syndrome: Anti-Ro
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus ... lupus nephritis ... searched for when ANA ... 40% Target: SS-A/Ro ... , neonatal lupus
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... activity Anti-Ro ... Ann Marie Kumfer ... #Systemic #Lupus
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... lesions • Anti-Ro ... • Anti-Smith, Ro ... + (+) anti-Ro/SSA
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... , Drug-induced Lupus ... erythematosus (SLE ... erythematosus (SLE
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... Lupus (DIL): ... Workup: - ANA ... #sle #comparison
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus (SLE ... , Drug-induced Lupus ... erythematosus (SLE ... erythematosus (SLE ... (SLE), Systemic
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Anti-SSA (Ro),
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... , oral ulcers, Lupus ... Workup: - ANA ... #lupus #Systemic