13 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Differential Diagnosis Algorithm ... Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... ↑ LDH • Anti-RBC ... C3d • Blood smear ... Anemia #diagnosis #management ... #treatment #rheumatology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... on Smear • Chronic ... Spherocytes on Smear ... Non-lmmune #Anemia #Classification ... #Causes #Hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Differential Diagnosis Algorithm ... Initial Workup: CBC ... acid, peripheral smear ... ↑ Destruction (hemolysis ... #hematology #workup
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Algorithm Suspected ... Initial labs: CBC ... Reticulocytes, smear ... #Algorithm #hematology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... lysis → severe hemolytic ... phase: Peripheral smear ... TREATMENT: ​• Acute ... Fever #diagnosis #management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Peripheral Smear ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Differential #Diagnosis #Algorithm
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... Vmphocytosis on routine CBC ... transformation) Treatment ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... incidentally via CBC ... • Treatment algorithms ... PV #Diagnosis #Management ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Peripheral smear ... + Bleeding Treatment ... hydration • RBC ... diagnosis #causes #treatment ... #management #hematology