9 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... Clinical TLS: • AKI ... #TLS #diagnosis ... #management #oncology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
- Differential Diagnosis ... Rhabdomyolysis • Tumor lysis ... syndrome • Metabolic ... Elimination: • AKI ... blockers - MCW Nephrology
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
- Differential Diagnosis ... Rhabdomyolysis, Tumor lysis ... syndrome, Hemolysis ... Kidney Disease: • AKI ... #phosphate #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Workup Algorithm ... and Differential Diagnosis ... clinical context and signs ... • Cardio-renal syndrome ... #Workup #Algorithm
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Syndrome Leukostasis ... fever - ACS, AKI ... WBC >100k, + lab signs ... hydration - Hyperkalemia ... #diagnosis #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Acidosis, Cell Lysis ... , RTA Type IV, AI ... reabsorption) Workup ... #Diagnosis #Management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Framework and Management ... declines > ALT) • AKI ... + myoglobin AKI ... #Management #causes
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... hypertension and signs ... renal bruit or signs ... Neurologic disorders
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
hyperthermia crisis (late sign ... • Serotonin syndrome ... Phaeochromocytoma Neurologic ... Anesthesia #Checklist #Diagnosis ... #Management #Workup