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differential management erythematosus systemic ana antinuclear antibodies autoantibodies classification disease signs symptoms table activation algorithm anca antibody antineutrophil antiphospholipid aortitis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Antiphospholipid-antibody syndrome ... • Vasculitis ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Polymerase Ill • ANCA Vasculitis ... Autoantibodies #Rheumatology ... #diagnosis #associations
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... arteritis, Cogan's Syndrome ... (RA), Systemic lupus ... erythematosus (SLE ... #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... Labs/Diagnosis: ... (e.g. systemic lupus ... erythematosus (SLE ... classification #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Differential Diagnosis ... Clinical Features ... #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... Demyelinating Syndrome ... Erythematosus #SLE ... CNS #neurology #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... is clinically suspected ... overlap syndromes ... erythematosus #diagnosis ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
microscopy and serial ... likely it will be clinically ... ), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... Thrombosis and arterial ... such as systemic lupus ... , and SLE) • Urinalysis ... #rheumatology #
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