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diagnosis rheumatology ana causes patterns antibody erythematosus obstetrics systemic testing antibodies autoantibodies cytoplasmic nuclear abortion arthropathies arthropathy bradycardia dermatology disorders
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Farr assay) and lupus ... with MCTD and Raynaud's ... Lupusreference #Antinuclear
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... erythematosus (SLE ... erythematosus (SLE ... Kumfer @AnnKumfer #Antinuclear ... rheumatology #diagnosis #differential
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... • Specific for SLE ... #Systemic #Lupus
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... SSc, PM/SSc OS, Raynaud ... CTD-ILD, IIM, Raynaud ... ARUPLabs #ANA #Antinuclear ... Cytoplasmic #Patterns #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... erythematosus (SLE ... (SLE), Systemic ... Kumfer @AnnKumfer #Antinuclear ... rheumatology #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Photosensitivity 29% - Raynaud's ... involvement 3% SLE-Related ... (aPL) 30-45% Differential ... Lupusreference #SLE ... symptoms #mimickers #differential
Causes of Recurrent Pregnancy Loss - Differential Diagnosis Algorithm Environmental: • Toxin (organic solvents, mercury, lead) •
Pregnancy Loss - Differential ... Diagnosis Algorithm ... Antiphospholipid syndrome • Lupus ... #Diagnosis #Algorithm ... Causes #Obstetrics #OBGyn
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... with Systemic Lupus ... Erythematosus (SLE ... #Diagnosis #Algorithm
Causes of Pelvic Mass - Differential Diagnosis Algorithm Gastrointestinal: • Appendiceal abscess • Diverticular abscess • Diverticulosis
Pelvic Mass - Differential ... Diagnosis Algorithm ... Hydrosalpinx Ovary: • See ... #Diagnosis #Algorithm ... Causes #Gynecology #OBGyn
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... AMA Speckled: • SLE ... CTD-ILD, IIM, Raynaud ... ARUPLabs #ANA #Antinuclear ... Cytoplasmic #Patterns #differential
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