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diagnosis rheumatology ana antibody differential patterns cytoplasmic erythematosus management nuclear systemic arthritis autoantibodies disease laboratory rheumatic rheumatoid sjogrens sle summary
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... severe disease Treatment ... #Systemic #Lupus
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Farr assay) and lupus ... with MCTD and Raynaud's ... Lupusreference #Antinuclear
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... SSc, PM/SSc OS, Raynaud ... CTD-ILD, IIM, Raynaud ... #Antibody #Testing
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Testing Cytoplasmic ... CTD-ILD, IIM, Raynaud ... ARUPLabs #ANA #Antinuclear ... #Antibody #Testing
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Testing - Nuclear ... SSc, PM/SSc OS, Raynaud ... ARUPLabs #ANA #Antinuclear ... #Antibody #Testing
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus (SLE) - Antinuclear ... - CCP antibody testing ... and C serology testing ... workup #diagnosis #testing
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... Cryoglobulinemia (4%-12%), Raynaud ... Adenocarcinoma Treatment
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