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diagnosis rheumatology management systemic erythematosus sle differential table druginduced laboratory neurology signs summary symptoms syndrome ana arthritis celiac cerebritis cns
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... with MCTD and Raynaud's ... with auto-immune diseases ... #autoantibodies
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... Treatment: • ... #Systemic #Lupus
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Photosensitivity 29% - Raynaud's ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... Erythematosus #Diagnosis #autoantibodies
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Cerebrovascular Disease ... the formation of autoantibodies ... Puncture, EEG Treatment ... diagnosis #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... months) and of autoantibodies ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... serum lgE, no autoantibodies ... (antinuclear antibodies ... IgG4 #Related #Disease ... management #phenotypes #workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... interstitial lung disease ... • Vascular: Raynaud's ... signs #symptoms #testing ... #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... joint • Systemic lupus ... erythematosus (SLE) - Antinuclear ... Arthritis #laboratory #workup
Commonly Used Diagnostic Tests for Celiac Disease Tissue transglutaminase (tTG) IgA antibodies - Most reliable noninvasive test
Tests for Celiac Disease ... patients with celiac disease ... Reflects response to treatment ... #Testing #Laboratory ... Tests #Diagnosis #Workup
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