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diagnosis rheumatology management ana differential erythematosus sle systemic antibody comparison cytoplasmic disease druginduced patterns table ambulatory arthritis bloodpressure clinic dil
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... with MCTD and Raynaud's ... specific for SLE (debated ... Lupusreference #Antinuclear ... #autoantibodies
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Photosensitivity 29% - Raynaud's ... involvement 3% SLE-Related ... Diagnosis and Lupus ... Erythematosus #Diagnosis #autoantibodies
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... severe disease Treatment ... #Systemic #Lupus
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... serum lgE, no autoantibodies ... (antinuclear antibodies ... Mettler_K1000 #IgG4 #Related ... management #phenotypes #workup
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... SSc, PM/SSc OS, Raynaud ... CTD-ILD, IIM, Raynaud ... #Antibody #Testing
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... constitutional symptoms • Treatment ... months) and of autoantibodies ... • Immunologic Workup ... life-threatening • Treatment
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Testing Cytoplasmic ... CTD-ILD, IIM, Raynaud ... rings: • HCV treated ... #Antibody #Testing
Clinic, Home, and Ambulatory Blood Pressure Measurements - Strengths and Weaknesses (via https://twitter.com/JACCJournals/status/1088104323354185730 ) Clinic Measurements: • BP measured
Patient should be seated ... , resting quietly ... used to guide treatment ... measured while seated ... BP measured at work
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus (SLE) - Antinuclear ... - CCP antibody testing ... Arthritis #laboratory #workup
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
disorders • Testing ... diazepam • EMG testing ... antibody that works ... CRP • Other autoantibodies ... Person Syndrome Treatment
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