16 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... severe disease Treatment ... #Systemic #Lupus
COVID-19 Diagnosis and Management Summary

 • Clinical Presentation
 • Testing
 • Imaging
 • Laboratory Findings
 •
Presentation • Testing ... • Imaging • Laboratory ... Findings • Treatment ... diagnosis #management #treatment ... #coronavirus #testing
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Farr assay) and lupus ... with MCTD and Raynaud's ... Lupusreference #Antinuclear
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Testing - Nuclear ... SSc, PM/SSc OS, Raynaud ... CTD-ILD, IIM, Raynaud ... #Antibody #Testing
COVID-19 Diagnosis and Management Summary
Clinical and laboratory testing
Lung Ultrasound
HRCT scan
In-hospital treatment
Severity assessment and respiratory support 
Post-mortem
Clinical and laboratory ... testing Lung Ultrasound ... scan In-hospital treatment ... Management #Summary #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... versus DIL • Laboratory ... life-threatening • Treatment ... Lupusreference #SLE #lupus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... calcium-b) • Laboratory ... constitutional symptoms • Treatment ... versus DIL • Laboratory ... life-threatening • Treatment
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
with response to treatment ... relapse No specific laboratory ... autoantibodies (antinuclear ... IgG4+ cells" Treatment ... phenotypes #workup #treatment
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... Testing Cytoplasmic ... CTD-ILD, IIM, Raynaud ... ARUPLabs #ANA #Antinuclear ... #Antibody #Testing
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus (SLE) - Antinuclear ... - CCP antibody testing ... more time for the laboratory ... Rheumatoid #Arthritis #laboratory