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Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... pattern: - SLE ... SSc, PM/SSc OS, Raynaud ... CTD-ILD, IIM, Raynaud ... ARUPLabs #ANA #Antinuclear
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... AMA Speckled: • SLE ... CTD-ILD, IIM, Raynaud ... conditions, SjS, SLE ... ARUPLabs #ANA #Antinuclear
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Erythematosus - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... with MCTD and Raynaud's ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE ... Lupusreference #Antinuclear
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Homogeneous pattern: • SLE ... pattern: • SjS, SLE ... SSc, PM/SSc OS, Raynaud ... ARUPLabs #ANA #Antinuclear
Raynaud's Syndrome - Washing off under hot water. Raynaud phenomenon is an exaggerated vasoconstrictive response of the
Raynaud's Syndrome ... Raynaud phenomenon ... #Raynauds #Syndrome
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 Raynaud's Syndrome - Washing off under hot water wath. Raynaud phenomenon is an exaggerated vasoconstrictive response of
Raynaud's Syndrome ... Raynaud phenomenon ... #Raynauds #Syndrome
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 Raynaud's Phenomenon on Physical Exam #Raynauds #Syndrome #disease #phenomenon #clinical #video #physicalexam #fingers #hands #rheumatology
Raynaud's Phenomenon ... Physical Exam #Raynauds
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 Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Cryoglobulinemia (4%-12%), Raynaud
Common Raynaud's Mimickers - Acrocyanosis - Chill blains (pernio) - Erythromelalgia - Frostbite - Achenbach's Syndrome Dr.
Common Raynaud's ... AnnKumfer #Common #Raynauds
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