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Raynaud's Syndrome - Washing off under hot water.
Raynaud phenomenon is an exaggerated vasoconstrictive response of the

Raynaud's Syndrome ... Raynaud phenomenon ... #Raynauds #Syndrome ... clinical #video #physicalexam

Raynaud's Syndrome - Washing off under hot water wath.

Raynaud phenomenon is an exaggerated vasoconstrictive response of

Raynaud's Syndrome ... Raynaud phenomenon ... #Raynauds #Syndrome ... clinical #video #physicalexam

Raynaud's Phenomenon on Physical Exam

#Raynauds #Syndrome #disease #phenomenon #clinical #video #physicalexam #fingers #hands #rheumatology

Raynaud's Phenomenon ... Physical Exam #Raynauds ... clinical #video #physicalexam

Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

- MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

-

Raynaud Phenomenon ... sclerosis, RA, SLE ... #Diagnosis #Reynaud

Raynaud's Phenomenon - Impaired finger circulation improved under warm water

#Raynauds #Phenomenon #Syndrome #clinical #video #physicalexam #rheumatology

Raynaud's Phenomenon ... warm water #Raynauds ... clinical #video #physicalexam

Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
• Associated

manifestations • Neonatal SLE ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE

Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
• Homogeneous pattern:
-

pattern: - SLE ... pattern: - SjS, SLE ... SSc, PM/SSc OS, Raynaud ... Speckled: - SLE ... CTD-ILD, IIM, Raynaud

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

Highly specific for SLE ... Association with both SLE ... with MCTD and Raynaud's ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE

Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin

Systemic Lupus (SLE ... defect (rare) Raynaud's ... Thrombocytopenia #Lupus #SLE

Systemic Lupus Erythematosus - Diagnosis
Manifestations:
- Arthritis 69%
- Malar rash 40%
- Fever 36%
-

Photosensitivity 29% - Raynaud's ... involvement 3% SLE-Related ... Lupusreference #SLE

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