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Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

 - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

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Raynaud Phenomenon ... sclerosis, RA, SLE ... #Diagnosis #Reynaud
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
manifestations • Neonatal SLE ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SLE ... pattern: - SjS, SLE ... SSc, PM/SSc OS, Raynaud ... Speckled: - SLE ... CTD-ILD, IIM, Raynaud
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... with MCTD and Raynaud's ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE
Ascites, pericardial effusion, and left pleural effusion on subcostal 4-chamber POCUS echocardiogram

Subcostal window in SLE patient.
subcostal 4-chamber POCUS ... Subcostal window in SLE ... effusion #s4c #POCUS ... echocardiogram #POCUS ... clinical #ultrasound #cardiology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... defect (rare) Raynaud's ... Thrombocytopenia #Lupus #SLE
Pulmonary Embolism on POCUS Echocardiogram

Mid 30's female with chest pain/dyspnea.  Triage EKG (no prior).
Pulmonary Embolism on POCUS ... See thread for POCUS ... POCUS (apical window ... Pulmonary #Embolism #POCUS ... A4c #clinical #cardiology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Photosensitivity 29% - Raynaud's ... involvement 3% SLE-Related ... Lupusreference #SLE
Ruptured Chordae Tendineae on POCUS Echocardiogram
 
Many underlying causes, not limited to: MVP, subacute endocarditis, connective
Chordae Tendineae on POCUS ... for MR when you see ... Chordae #Tendineae #POCUS ... Ultrasound #Clinical #Cardiology
Cardiac POCUS.  #diagnosis #em #cardiology #pocus
Cardiac POCUS. ... diagnosis #em #cardiology ... #pocus