743 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
→ ADH → water reabsorption ... #hyponatremia #comparison
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
↑ intestinal absorption ... ↑ bone reabsorption ... ↑ tubular reabsorption ... Hypophosphatemia: ↑ bone reabsorption ... ↓↓ tubular reabsorption
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
intestinal calcium absorption ... and stimulates resorption ... Stimulate calcium reabsorption ... kidney, Stimulates resorption
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
body water in comparison ... results in water reabsorption ... increased sodium reabsorption
Hypercalcemia - Hormones and Pathophysiology  
Calcitriol:
 • Bones: Enhances mineralization
 • GI Tract: ↑ Ca2+
Kidneys: ↑ Ca2+ reabsorption ... , ↑ PO4- reabsorption ... Kidneys: ↑ Ca2+ reabsorption ... , ↓ PO4- reabsorption ... , PO4- reabsorption
Fluid and Water Secretion and Absorption in the GI Tract

#Fluid #water #Secretion #Absorption #reabsorption #GITract #diagnosis
Secretion and Absorption ... water #Secretion #Absorption ... #reabsorption #
Proximal Renal Tubular Acidosis (RTA) Ttype 2 Overview

HCO3 reabsorptive failure
Lowering of threshold for HCO3 absorption in
Overview HCO3 reabsorptive ... threshold for HCO3 absorption
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Miscellaneous - Bone Resorption ... - Calcium Reabsorption
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
tubule (PCT) - Reabsorption ... Isosmotic reabsorption ... Secretion and reabsorption ... loop - Passive reabsorption ... (TAL) - Active reabsorption
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Bioavailability, Absorption ... #Pharmacology #Comparison