1556 results
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
compartment - b2-receptor ... - Anti-EGF receptors ... differential #diagnosis #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
mineralocorticoid receptor ... Vasopressin-2 (V2) receptor ... vasopressin-2 (V2) receptor ... Defects #Kidney #Nephrology
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
• mu- opioid receptor ... antagonist/k-receptor ... ) • k-opioid receptor ... Treatment #management #nephrology
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
Vasopressin - V1 receptor ... edgarvlermamd - Nephrology ... HepatoRenal #Syndrome #Nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Hypertonicity • ß2-receptor ... blockers - MCW Nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Mineralocorticoid Receptor ... ) Vasopressin Receptor ... Agonist V1 receptor-agonist ... Hypovolemic shock V2 receptor-agonist ... disorders Vasopressin Receptor
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
NS Vasopressor receptor ... • Blocks ADH receptor ... #hyponatremia #nephrology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Vasopressor receptor ... • Blocks ADH receptor ... #hyponatremia #nephrology
Pragmatic diagnostic algorithm for hypokalemia. 
***Typical presentations: 
 • Vomiting: urine Na/Cl > 1.6, low urine
mineralocorticoid receptor ... and angiotensin receptor ... differential #algorithm #nephrology
Central Nervous System Pharmacology - Somatic and Autonomic Receptors
Somatic
 • Rocuronium -> Non-depolarizing (reversible competitive inhibitors)
and Autonomic Receptors ... Ach -> Nicotinic Receptor ... -> Muscarinic Receptor ... -> Adrenergic Receptor ... -> Adrenergic Receptor