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diagnosis differential anemia disorders elevatedmcv lupus macrocytosis management thrombocytopenia cerebritis eosinophil eosinophilia erythematosus focal hcq hydroxychloroquine lad leukemia levels localized
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Autoimmune • ITP • SLE ... Foreign Surface (e.g ... #Causes #Hematology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... intake) • Target blood ... Insufficient blood ... (e.g. renal failure ... #rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG ... #rheumatology #
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Differential Diagnosis Algorithm ... • Infection (e.g ... #Causes #Hematology ... #Oncology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Differential Diagnosis Algorithm ... Iron Deficiency (Eg ... Blood Loss, Occult ... Other • e.g ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... • Secondary (e.g ... RA, SLE, PRV, Chronic ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
plateletcount), peripheral blood ... function test, ANA (e.g ... ., SLE), anti-phospholipid ... or if a primary hematologic ... #Workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Differential Diagnosis Algorithm ... Normal Blood Smear ... Increased Requirement (e.g ... #Causes #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... • Peripheral blood ... for secondary causes ... signs or symptoms (eg ... Differential #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... leukostasis syndrome: CNS ... #Leukemia #Hematology ... #Oncology #Diagnosis
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