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differential coagulation algorithm anemia bruising hemolytic abnormal aptt bleeding disseminated hemolysis management purpura thrombocytopenia treatment arterial atlas basics blanching bruise
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... coagulation (DIC ... hemoglobinuria (PNH) Extravascular ... #Extravascular ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... PK deficiency Intravascular ... • MAHA (TTP, DIC ... #Hemolysis #Intravascular ... #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Disseminated intravascular ... coagulation (DIC ... #Causes #diagnosis ... #differential #hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... - Differential Diagnosis ... artery aneurysm: Causes ... - Disseminated intravascular ... coagulation (DIC
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
for Disseminated Intravascular ... Coagulation (DIC ... #Disseminated #Intravascular ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Thrombocytopenia • Prolonged ... #Disseminated #Intravascular ... #Coagulation #diagnosis ... #management #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... for a Prolonged ... intravascularcoagulation (DIC ... #Causes #diagnosis ... #differential #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... IVIG infusion Intravascular ... : TTP, HUS, DIC, ... #Differential #Diagnosis ... #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... - Differential Diagnosis ... . prolonged/induced ... • Disseminated intravascular ... coagulation (DIC
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... as disseminated intravascular ... count, D-dimer, egg ... hemolytic #anemia #Hematology
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