18 results
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
cryoglobulinemia vasculitis - Diagnosis ... remission - Refractory ... associated with refractory ... disease Dr. ... Cryoglobulinemia #Vasculitis #Rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
artery aneurysms Diagnosis ... ) Differential Diagnosis ... azathioprine • Severe or refractory ... Behcet #Syndrome #diagnosis ... signs #symptoms #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... Refractory ITP, ... #Differential #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... opacities • Diagnosis ... • Differential Diagnosis ... dysfuxtion, ICU, refractory ... #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Auto-amplification loop Diagnosis ... • Autoimmune diseases ... Adult-onset Still disease ... treatment #summary #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Myeloproliferative disease ... Venous #Arterial #pathophysiology ... #hematology #differential ... #diagnosis #vascular
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... • Severe Liver Disease ... #Coagulation #diagnosis ... treatment #management #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... • Autoimmune diseases ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology ... #pathophysiology