36 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... -> AML: Blast crises ... - infiltrates (anemia ... ) CLL Symptoms: ... #Oncology #Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Autoimmune • ITP • SLE ... • CLL • APLA ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Orange or Hep C Clinical ... with no early symptoms ... • Neutropenia, anemia ... microglobulin Treatment
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... marrow failure with anemia ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... • Treatment: ... Systemic Lupus Erythematosus ... comparison #table #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... ) Blood (75%): Anemia ... #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... autoantibodies that will cause ... #SLE #CNS #neurology ... #rheumatology #
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology