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diagnosis differential hematology causes sle algorithm classification dermatology erythematosus management oncology criteria pain signs symptoms syndrome systemic testing approach cardiology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... ) Blood (75%): Anemia ... Leucopenia/lymphopenia, Thrombocytopenia ... symptoms #diagnosis #rheumatology
Seronegative Inflammatory Arthritis - Differential Diagnosis • Seronegative Rheumatoid Arthritis • Infectious Arthritis: Viral, Bacterial,
• Infectious Arthritis ... Disease: Systemic Lupus ... Erythematous, Systemic Vasculitis ... , Reactive Arthritis ... #Diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Hypersensitivity vasculitis ... lesions • Discoid lupus ... #dermatology #joint ... differential #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Lyme), reactive arthritis ... SLE, psoriatic arthritis ... #rheumatology # ... approach #workup
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Lyme disease, Vasculitis ... Heberden's nodes (DIP joints ... Bouchard's nodes (PIP joints ... differential #diagnosis #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
INVOLVING 2 OR MORE JOINTS ... NEUROLOGIC - HEMOLYTIC ANEMIA ... (<1000/MM3) - THROMBOCYTOPENIA ... absence of hemolytic anemia ... #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... : Giant Cell Arteritis ... ANCA associated vasculitis ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Arthritis of the Hand - Arthritis Patterns Osteoarthritis: • Osteoarthritis of the hand usually involves the DIP and
the DIP and PIP joints ... the PIP and MCP joints ... but not the DIP joints ... PsA, Sickle cell anemia ... hand #diagnosis #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
large vessels - Arteritis ... temporalis (giant-cell arteritis ... - Takayasu arteritis ... - systemic lupus ... Vessels #Diagnosis #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... • Arthritis domain ... in at least 2 joints ... domain: Leukopenia, Thrombocytopenia ... Erythematosus #diagnosis #rheumatology
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