18 results
Immunosuppressive Medications in Systemic Lupus Erythematosus (SLE)
 - MTX (oral, subcutaneous)
 - AZA (oral) 
 -
Immunosuppressive Medications ... in Systemic Lupus ... Erythematosus ( ... #Erythematosus ... #treatment
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
half-life = 40 days ([HCQI ... 200ng/mL Best indications ... Hydroxychloroquine #HCQ ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Puncture, EEG Treatment ... #Erythematosus ... CNS #neurology #rheumatology ... diagnosis #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... life-threatening • Treatment ... #Systemic #Erythematosus ... Management #Summary #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #Systemic #Lupus ... #Erythematosus ... Summary #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematosus) ... erythematosus ( ... Non-autoimmune rheumatologic ... activation and/or medications ... #Diagnosis #Rheumatology
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Erythematosus ... for 1 year of treatment ... Lupusreference #DrugInduced ... #medications #drugs ... differential #diagnosis #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Erythematosus ( ... life-threatening • Treatment ... Lupusreference #druginduced ... #table #rheumatology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Algorithm Congenital Medications ... Destruction • Systemic Lupus ... Erythematosus ... Algorithm #Causes #Hematology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... recommended with other medications ... Hydroxychloroquine #hcq ... Risks #Benefits #Lupus ... #sideeffects #rheumatology