22 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
to Kidney: Anti-GBM ... involvement: Anti-GBM ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... workup, including BM ... Thrombocytosis #Platelets #Differential ... #Diagnosis #Algorithm
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Splenomegaly - Differential ... Diagnosis Algorithm ... Bacterial • Viral (EBV ... #Diagnosis #Algorithm ... #Causes #Hematology
A summary of GI Lymphomas - Primary Lymphoid Neoplasms of the GI Tract
T-Cell
 - EATL
 -
GIT B-Cell - EBV ... Lymphomas #GITract #hematology ... hemepath #pathology #differential ... #diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Lymphadenopathy - Differential ... Diagnosis Algorithm ... Infectious • EBV ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... Diagnosis Framework ... Viral: HIV, HCV, EBV ... #Diagnosis #Framework ... #hematology
Differential Diagnosis of Hypoglycemia
Evaluation of Hypoglycemia
Patients with known diabetes who are not systemically ill and can
Differential Diagnosis ... can identify a clear ... insulin antibodies #Diagnosis ... #EM #IM #Hypoglycemia ... #Differential #
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... Coxsackie, CMV, EBV ... Stills #Disease #diagnosis ... management #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... treatment #summary #rheumatology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... Illness Myopathy (ICU ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis