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diagnosis rheumatology table autoantibodies erythematosus lupus management systemic ana antibodies antinuclear associations coronavirus covid19 diseases sle summary abscess anca antibody
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anti-Smith, Anti-Ro ... Syndrome: Anti-Ro
Reproductive Number (R0 "R Naught") showing how contagious / transmissible a pathogen is. The R0
Fatality 2-3% ** 'Ro ... Reproductive #Number #R0 #Ro
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
SLE Anti-SSA (Ro
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
activity Anti-Ro
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-Ro/SSA
Abscess Scan with Debris on Point of Care Ultrasound (POCUS) Few moments on my shift compare to
Rescan ro make sure
►
 SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
lesions • Anti-Ro ... • Anti-Smith, Ro ... ANA + (+) anti-Ro
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
40% Target: SS-A/Ro
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Antibodies: Anti-Ro ... Antibodies: • Anti-Ro
COVID-19 - A Seattle Intensivist's One-Page Cheat-Sheet on COVID-19 v2.7 Updated March 26 2020 (v2.7) incorporating newer
rate = 30-40% • Ro
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