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rheumatology management differential neurology ana antinuclear erythematosus lupus systemic sle algorithm anca ankle antibody antineutrophil autoantibodies classification clinical cord diseases
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
and Clinical Findings ... RA) or systemic lupus ... / Symptoms: - ... #Diagnosis #Signs ... #Symptoms
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... ) • Systemic lupus ... • Sjögren syndrome ... Anti-Ro/SSA ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... erythematosus (SLE), Sjogren's ... Syndrome (SS), ... #rheumatology #diagnosis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... 40% Target: SS-A/Ro ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... : Anti-Ro/SSA & ... salivary ducts Clinical ... phenomenon (16%) MSK
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... dermatomyositis, Sjogren ... Clinical Features ... : • Symptoms limited
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... disorders (Systemic lupus ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Autoimmune: thyroid, Sjogren ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... Myasthenia #Gravis #diagnosis
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
renal failure Clinical ... are not caused ... skin (16-32%): lupus ... anterior/posterior MSK ... #Management #Signs
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