70 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... Anti-Smith, Anti-Ro ... Polymerase Ill • ANCA ... Vasculitis: P-ANCA ... perinuclear), C-ANCA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... Anti-Ro/SSA ... MPO: 75-80% - ANCA ... Jcortesizaguirr #ANA
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and ... Disease Associations ANA ... SLE Anti-SSA (Ro ... Graves' disease c-ANCA ... granulomatosis p-ANCA
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... lesions • Anti-Ro ... Diagnosis: • ANCA-associated ... Serositis Labs: • ANA ... antibodies • (-) ANA
This is what a shoulder dislocation looks like on US before and after reduction. Focus on
like on US before and ... Focus on the joint ... space and watch ... EM_RESUS #Clinical #POCUS ... #MSK #Shoulder
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Antinuclear (ANA ... activity Anti-Ro ... Ann Marie Kumfer
Flexor Tenosynovitis (FTS)

The clinical diagnosis of FTS is made using Kanavel’s Signs:
 - Fusiform swelling.
 -
Infographic by Anna ... Criteria #Sign #Hand #MSK
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies and ... with Farr assay) and ... searched for when ANA ... 40% Target: SS-A/Ro ... rheumatology #table #ANA
Talus Fracture on POCUS
Athlete with hard landing on one foot, pain and tenderness over dorsum of
Talus Fracture on POCUS ... one foot, pain and ... POCUS showed talus ... Talus #Fracture #POCUS ... clinical #ultrasound #MSK
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
dehydrogenase, and ... Serology: - Anti-Ro ... /SSB, anti-Sm, and ... - (Vasculitis) ANCA ... C serologies, and