57 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... Polymerase Ill • ANCA ... Vasculitis: P-ANCA ... perinuclear), C-ANCA ... #associations #table
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... Anti-Ro/SSA ... involvement - PR3>MPO - ANCA ... MPO: 75-80% - ANCA
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... SLE Anti-SSA (Ro ... Graves' disease c-ANCA ... granulomatosis p-ANCA ... diseases #diagnosis #table
ANCA Vasculitis - GPA, MPA, Eosinophilic GPA

doi:10.1038/s41572-020-0204-y

#ANCA #Vasculitis #GPA #MPA #Eosinophilic #rheumatology #diagnosis #comparison #table
ANCA Vasculitis ... s41572-020-0204-y #ANCA ... diagnosis #comparison #table
Effects of Strokes by Location - Anterior vs Posterior Localization

Anterior Circulation 
 - MCA 
 -
- MCA - ACA ... circulation - ASA ... - PICA - AICA ... Neurology #Diagnosis #Table
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
with Farr assay) and ... searched for when ANA ... 40% Target: SS-A/Ro ... #rheumatology #table ... #ANA
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... lesions • Anti-Ro ... Diagnosis: • ANCA-associated ... Serositis Labs: • ANA ... antibodies • (-) ANA
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Antinuclear (ANA ... activity Anti-Ro ... Ann Marie Kumfer
Reproductive Number (R0 "R Naught") showing how contagious / transmissible a pathogen is.  The R0
, MERS, Ebola) and ... Fatality 2-3% ** 'Ro ... is preliminary and ... Reproductive #Number #R0 #Ro ... coronavirus #comparison #table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... - Rare - pANCA ... Workup: - ANA ... 50-60% - pANCA ... sle #comparison #table