37 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus (SLE ... Anti-Smith, Anti-Ro ... Syndrome: Anti-Ro ... Vasculitis: P-ANCA ... perinuclear), C-ANCA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antibody) and ANCA ... in drug-induced SLE ... Anti-Ro/SSA ... 80-90%) > MPO - ANCA ... MPO: 75-80% - ANCA
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Anti-SSA (Ro), ... Graves' disease c-ANCA ... granulomatosis p-ANCA
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Antinuclear (ANA ... activity Anti-Ro ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... searched for when ANA ... 40% Target: SS-A/Ro ... higly specific for SLE ... rheumatology #table #ANA
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lesions • Anti-Ro ... • Anti-Smith, Ro ... + (+) anti-Ro/SSA ... can rule in SLE
Pulmonary Embolism on POCUS Echocardiogram

Mid 30's female with chest pain/dyspnea.  Triage EKG (no prior).
Pulmonary Embolism on POCUS ... See thread for POCUS ... POCUS (apical window ... Pulmonary #Embolism #POCUS ... Echocardiogram #A4c
Ascites, pericardial effusion, and left pleural effusion on subcostal 4-chamber POCUS echocardiogram

Subcostal window in SLE patient.
subcostal 4-chamber POCUS ... Subcostal window in SLE ... pericardial #effusion #s4c ... #POCUS #echocardiogram ... #POCUS #clinical
Apical 3-Chamber (A3C) View - Regional Wall Anatomy on POCUS Echocardiogram

The apical 3-chamber has essentially the
Apical 3-Chamber (A3C ... Wall Anatomy on POCUS ... Because you can see ... UAlberta_Sono #A3C ... Wall #Anatomy #POCUS
Mitral Valve Endocarditis on POCUS Echocardiogram
66 yo presents with petechiae to lower extremities. Pt had mitral
Endocarditis on POCUS ... #POCUS give you ... Here you see a vegetation ... #Endocarditis #POCUS ... clinical #cardiology #a4c