16 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus (SLE ... Anti-Smith, Anti-Ro ... Syndrome: Anti-Ro ... Vasculitis: P-ANCA ... perinuclear), C-ANCA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antibody) and ANCA ... in drug-induced SLE ... Anti-Ro/SSA ... 80-90%) > MPO - ANCA ... MPO: 75-80% - ANCA
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Anti-SSA (Ro), ... Graves' disease c-ANCA ... granulomatosis p-ANCA
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Antinuclear (ANA ... activity Anti-Ro ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... searched for when ANA ... 40% Target: SS-A/Ro ... higly specific for SLE ... rheumatology #table #ANA
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lesions • Anti-Ro ... • Anti-Smith, Ro ... + (+) anti-Ro/SSA ... can rule in SLE
Anterior Shoulder Dislocation Pre and Post-Reduction on Point of Care Ultrasound (POCUS)

Using #POCUS to identify an
Care Ultrasound (POCUS ... ) Using #POCUS ... Do you see the needle ... Dislocation #Reduction #POCUS ... Ultrasound #Cinical #MSK
TISSUE APPEARANCES ON 
MUSCULOSKELETAL ULTRASOUND 

Bone:
 
Bone is represented as a very bright structure and appears
image as you can see ... You can see here ... MUSCULOSKELETAL #MSK ... #POCUS #Atlas #
Biceps Rupture and Hematoma on POCUS

Dr. Ana Segura @anaseguragrau

#Biceps #Rupture #Hematoma #POCUS #MSK #ultrasound #clinical
and Hematoma on POCUS ... Ana Segura @anaseguragrau ... Rupture #Hematoma #POCUS ... #MSK #ultrasound
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Antibodies: Anti-Ro ... Antibodies: • Anti-Ro ... phenomenon (16%) MSK