984 results
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... Associated with SCLE ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SLE ... pattern: - SjS, SLE ... Speckled: - SLE ... conditions, SjS, SLE ... Golgi/polar: - SLE
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Diagnosis Algorithm ... Autoimmune • ITP • SLE ... Thrombocytopenia #Differential ... #Diagnosis #Algorithm
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... syndrome Anti-Scl ... Diffuse) Anti-Sm - SLE
Causes of Secondary IgA Nephropathy - Differential Diagnosis Algorithm
 • GI disorders: Celiac disease, Crohn's disease,
Nephropathy - Differential ... Diagnosis Algorithm ... spondylitis, RA, SLE ... Nephropathy #Causes #Differential ... #Diagnosis #Algorithm
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
retinal exudates) - SLE ... nodules - RA, SLE ... disease - RA - SLE ... • Seizures - SLE ... #joint #pain #differential
Causes of Polyneuropathy - Differential Diagnosis Algorithm
 • Metabolic: DM, Hypothyroidism, CKD, Cirrhosis, Nutritional deficiency
 •
Polyneuropathy - Differential ... Diagnosis Algorithm ... Paraneoplastic, CTD (SLE ... Polyneuropathy #Differential ... #Diagnosis #Algorithm
Dysphagia - Differential Diagnosis Algorithm

Oropharyngeal Dysphagia 
Esophageal Dysphagia 
 • Upper 2/3 (striated muscle): stroke, NMJ
Dysphagia - Differential ... Diagnosis Algorithm ... muscular atrophy, SLE ... #Dysphagia #Differential ... #Diagnosis #Algorithm
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... erythematosus (SLE ... erythematosus (SLE ... rheumatology #diagnosis #differential
Cutaneous Lupus Erythematosus
 • Acute Cutaneous Lupus (ACLE)
 • Neutrophilic Dermatoses 
 • Vascular Lesions
 •
Cutaneous Lupus (ACLE ... Cutaneous Lupus (SCLE ... Cutaneous Lupus (ICLE ... Cutaneous Lupus (CCLE