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differential clinical rheumatology cardiology causes ultrasound echocardiogram management lupus erythematosus systemic s4c hematology pulmonary lung neurology classification evaluation signs symptoms
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Associated with SCLE ... Associated with SLE-SSc-AlM ... patients with typical SLE ... erythematosus #diagnosis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Diffuse) Anti-Sm - SLE ... Associations #diseases #diagnosis
Cutaneous Lupus Erythematosus • Acute Cutaneous Lupus (ACLE) • Neutrophilic Dermatoses • Vascular Lesions •
Cutaneous Lupus (ACLE ... Cutaneous Lupus (SCLE ... Cutaneous Lupus (ICLE ... Cutaneous Lupus (CCLE ... Erythematosus #diagnosis
Clinical Manifestations of Systemic Lupus Erythematosus (SLE) #Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... Erythematosus #SLE ... #Rheumatology #Diagnosis
Ascites, pericardial effusion, and left pleural effusion on subcostal 4-chamber POCUS echocardiogram Subcostal window in SLE patient.
subcostal 4-chamber POCUS ... Subcostal window in SLE ... pericardial #effusion #s4c ... #POCUS #echocardiogram ... #POCUS #clinical
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 Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... pattern: - SjS, SLE ... Speckled: - SLE ... conditions, SjS, SLE ... #differential #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... is rare in DIL, SCLE-DIL ... Erythematosus (SLE ... are evocative of SLE ... druginduced #lupus #sle
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
retinal exudates) - SLE ... nodules - RA, SLE ... disease - RA - SLE ... • Seizures - SLE ... #differential #diagnosis
Pulmonary Embolism on POCUS Echocardiogram Mid 30's female with chest pain/dyspnea. Triage EKG (no prior).
Pulmonary Embolism on POCUS ... Differential/diagnosis ... See thread for POCUS ... POCUS (apical window ... Echocardiogram #A4c
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 Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Algorithm Decreased ... Autoimmune • ITP • SLE ... #Differential #Diagnosis ... #Algorithm #Causes
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