22 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SjS ... Raynaud phenomenon, SjS ... PBC/SSc OS, PBC/SjS ... Speckled: - SLE, SjS ... polar: - SLE, SjS
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs SJS ... lymphocytes and eos SJS ... DRESS #Syndrome #SJS ... TEN #comparison #table
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... PBC/SSc OS, PBC/SjS ... Speckled: • SLE, SjS ... Neurologic conditions, SjS ... polar: • SLE, SjS
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
Comparison - DRESS | SJS ... target lesions SJS ... Rashes #Comparison #TABLE
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
Rash - Diagnostic Algorithm ... (Strep/Staph), SJS ... or Pustular: SJS ... Febrile #Diagnosis #Algorithm
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Sjogren's Syndrome (SS ... Kumfer @AnnKumfer #Antinuclear
Comparison - Serotonin Syndrome, Neuroleptic Malignant Syndrome, and Malignant Catatonia

- BWH Medicine Chiefs @BrighamChiefs

#Serotonin #Syndrome #Neuroleptic
Catatonia #NMS #SS ... management #treatment #table
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... Speckled pattern: • SjS ... Raynaud phenomenon, SjS ... ARUPLabs #ANA #Antinuclear
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... 30-40% Target: SS-A ... Lupusreference #Antinuclear ... #rheumatology #table
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
Maculopapular Rashes - THE ALGORITHMIC ... macule and papule (Table ... pathognomonic for SJS ... Maculopapular #Rash #Algorithm