22 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Testing - Nuclear ... #Antibody #Testing ... #differential #diagnosis ... #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
SLE), Sjogren's Syndrome ... Kumfer @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... Testing - Nuclear ... : • SjS, SLE, DM ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... Testing Cytoplasmic ... Patterns Reticular ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... SLE), Sjogren's Syndrome ... (SS), Polymyositis ... #patterns #rheumatology ... #diagnosis #differential
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... B12 - Anti-IF Antibodies ... B12 - Anti-IF Antibodies ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... Alloimmune • anti-HLA antibodies ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antineutrophil cytoplasmic antibodies ... cases • Sjögren syndrome ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... Cold Agglutinin Syndrome ... anemia • Cold ... Positive Coombs testing ... #hematology #diagnosis
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... HLH syndrome 5. ... Eating disorders ... Acquired Aplastic Anemia ... #Algorithm #Hematology