118 results
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Antinuclear Antibody (ANA ... Pleuritis) H Hematologic ... Arthritis R Renal Disease ... IMDAMNSHARP #sle #systemic ... erythematosus #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... Sjogren's Syndrome (SS ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... SSc: systemic sclerosis ... arthritis SLE : systemic ... #Differential #Comparison ... Table #Pulmonary #Rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... arthritis, Skin rash ... solid cancers • Systemic ... diagnosis #management #treatment ... #rheumatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs SJS ... : 2-8 weeks • Rash ... : 4-28 days • Rash ... #TEN #comparison ... #table #dermatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Disease! ... • Homogeneous: Systemic ... ) • Speckled: Systemic ... Sjogren's Syndrome (SS ... #patterns #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... • Azathioprine and ... : • Systemic steroids ... #pharmacology #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... can present with rash ... including heliotrope rash ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... Treatment: • ... Ann Marie Kumfer ... Summary #diagnosis #rheumatology