36 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Vesicopustule on erythematous ... Discoid lupus erythematosus ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... severe disease Treatment ... diagnosis #rheumatology ... #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... rashErythematous ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... #Diagnosis #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... autoantibodies that will cause ... #rheumatology # ... cerebritis #diagnosis #management ... #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Systemic Lupus Erythematosus ... Manifestations: Malar rash ... comparison #table #rheumatology ... #diagnosis #management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... #systemic #erythematosus ... symptoms #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... • Ulcerated, erythematous ... #rash #diagnosis ... #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... 6) An annular rash ... lupus #diagnosis #sle ... #erythematosus # ... rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... Edema in 70% of cases ... Skin involvement ... drug reaction • SJS ... disease: symptomatic treatment