11 results
differential management hematology antibody antinuclear druginduced erythematosus nuclear patterns syndrome activation antiphospholipid apls bleeding classification clinicopathology clues comparison cytoplasmic dil
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody Testing ... Scl70 (in some cases ... Antinuclear #Antibody #Testing ... #differential #diagnosis ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Manifestations: Malar rash ... Positive in 60-80% of cases ... Erythematosus #Diagnosis ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Discontinuation of causal ... Workup: - ANA ... #table #rheumatology ... #diagnosis #management
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... many differential diagnoses ... annular rash on ... #diagnosis #sle ... erythematosus #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody Testing ... Speckled pattern: • SjS ... , SLE, DM, SSc, ... #differential #diagnosis ... #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... - Differential Diagnosis ... discern these causes ... testing factor ... #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
manifestations: from easy bruising ... Petechial or purpuric rash ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... mucositis - Rash ... such as systemic lupus ... SLE) • Urinalysis ... #rheumatology #
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
NPSLE rare, Malar rash ... is rare in DIL, SCLE-DIL ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup Algorithm ... chromosomal causes ... : • Lupus Anticoagulant ... Hypercoagulable #Workup #Algorithm ... #diagnosis #hematology
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