30 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... pattern: - SjS ... Antinuclear #Antibody #Testing ... #differential #diagnosis ... #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... /full triad at diagnosis ... after 2 years of treatment ... #rheumatology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... awaiting confirmatory testing ... thrombocytopenia #Comparison #Diagnosis ... #Table #Hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Conjunctivitis, Mucositis, Rash ... Criteria - Fever lasting ... Polymorphous rash ... KD #vasculitis #rheumatology ... #management #treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
with urticarial rash ... Rash: • Nonpruritic ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders Testing ... INDICATIONS FOR TESTING ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... Differential Diaqnoses ... Stills #Disease #diagnosis ... #management #treatment ... #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody Testing ... PBC/SSc OS, PBC/SjS ... Antinuclear #Antibody #Testing ... #differential #diagnosis ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
, difficult to diagnose ... maculopapular rash ... synovitis (40%) Treatment ... Disease #AOSD #rheumatology ... #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
testing for HLH-associated ... • Bicytopenia Treatment ... Supportive measures and treating ... #management #treatment ... #hematology