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diagnosis ana dermatology patterns testing algorithm antibody erythematosus lupus sle adultonset antibodies cytoplasmic disease management myopathy myositis nuclear stills systemic
Fever and Rash - Differential Diagnosis Framework • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... Differential Diagnosis ... Noninfectious: SJS ... Medicine @SCVMCMed #Fever ... #Rash #Differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... pattern: - SjS ... ARUPLabs #ANA #Antinuclear ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
skin syndrome (SSS ... Nikolsky sign, the differential ... erythematous rash ... #Erythematous #Rash ... #Differential
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Sjogren's Syndrome (SS ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial Rash ... - Differential ... Red Flags: • Fever ... Measurement of antinuclear ... #Differential #
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... PBC/SSc OS, PBC/SjS ... ARUPLabs #ANA #Antinuclear ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... • Rheumatic fever ... #skin #rashes #differential ... #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... arthritis, Skin rash ... fraction < 20% Differential ... management #treatment #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Speckled pattern: • SjS ... Raynaud phenomenon, SjS ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... 40% - Fever 36% ... (aPL) 30-45% Differential ... symptoms #mimickers #differential ... #rheumatology
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