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SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... ELISA) - Anti-Sm ... of antibody to Sm ... #Rheumatology #SLE
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... (Diffuse) Anti-Sm ... - SLE Anti-SSA
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Anti-dsDNA, Anti-Sm ... #IMDAMNSHARP #sle
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... phenomenon Anti-Sm ... is clinically suspected ... higly specific for SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... to 1:1 F:M • Clinical ... cutaneous DIL), anti-Sm ... Erythematosus (SLE ... 40, F:M 9:1 • Clinical
Trichomonas on Urine Microscopy Trichomonas organism adjacent to WBC’s and a macrophage - brightfield with SM stain
brightfield with SM ... trichomoniasis #clinical
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 Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
involvement 3% SLE-Related ... 15-30% - Anti-Sm ... Lupusreference #SLE
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... pattern: - SjS, SLE ... UCTD - Smith, Sm ... Speckled: - SLE ... conditions, SjS, SLE
Trichomonas on Urine Microscopy Trichomonas organisms adjacent to mixed cellular cast containing WBC's, tubular epithelial cells, and
brightfield with SM ... trichomoniasis #clinical
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 Clinical Manifestations of Systemic Lupus Erythematosus (SLE) #Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... Erythematosus (SLE ... Erythematosus #SLE
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