1580 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
) and Anti-La (SSB ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... : Anti-Ro (SSA), ... Systemic Sclerosis, SSc
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
SLE), Sjogren's Syndrome ... (SS), Polymyositis ... or scleroderma (SSc
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... PSS: Sjogren syndrome
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
lupus (90%) Anti-SSA ... 30-40% Target: SS-A ... Sjogren Anti-SSB ... Associated with SLE-SSc-AlM ... overlap syndromes
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
SLE), Sjogren's Syndrome ... (SS), Polymyositis ... or scleroderma (SSc ... Arthritis, Sjögren Syndrome
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SLE, SSc ... SjS, SLE, DM, SSc ... , PM/SSc OS, MCTD ... pattern: - SSc ... , PBC/SSc OS
Superior Vena Cava Syndrome on Physical Exam

Prominent dilated collateral veins are seen bypassing the SVC obstruction

#SVC
Superior Vena Cava Syndrome ... bypassing the SVC ... obstruction #SVC ... Superior #Vena #Cava #Syndrome
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anticentromere - CREST syndrome ... Anti-Sm - SLE Anti-SSA ... (Ro), Anti-SSB ... La) - Sjogren's syndrome ... Goodpasture's syndrome
Algorithm for Suspected SVC Syndrome

SVC syndrome suspected: Facial/arm/neck edema, distended neck/chest veins, facial plethora, dyspnea, cough,
for Suspected SVC ... Syndrome SVC ... syndrome suspected ... Syndrome Grading ... #Syndrome #Algorithm
POCUS Echocardiography - Table of Cardiac Views and Windows
 • Parastemal Long-Axis View (PLAX)
 • Parasternal
• Subcostal (SC ... Inferior Vena Cava (SC ... View (A5C) • SC ... Suprasternal Notch (SSN ... View (A3C) • SSN