42 results
diagnosis differential symptoms erythematosus management sle systemic hematology neurology ana antibodies antinuclear autoantibodies classification complications table arthritis autoimmune dermatology manifestations
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... - Budd Chiari Syndrome ... Complications #pathophysiology ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... LAC) • Sjogren Syndrome ... Peptide (CCP) • Myositis ... Polymerase Ill • ANCA Vasculitis
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... TIF1y, NXP2, Mi-2, SAE ... Anti-Synthetase Syndrome ... Inclusion Body Myositis ... clinical #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Normal CK - Myositis ... #Systemic #Lupus ... Complications #pathophysiology ... #signs #symptoms
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Churg-Strauss syndrome ... - systemic lupus ... - Schnitzler syndrome ... - Sjögren syndrome ... Vessels #Diagnosis #Rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... #diagnosis #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Other brainstem syndromes ... • Transverse myelitis ... positive NMO only): Myositis ... disorders (Systemic lupus ... neurology #symptoms #signs
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
• Acute stroke syndromes ... Inflammatory: Vasculitis ... Paraneoplastic syndrome ... Lambert-Eaton - Isaacs' syndrome ... Lack of UMN/LMN signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... Conjunctivitis, mucositis ... such as systemic lupus ... purpura: strong sign ... differential #diagnosis #rheumatology
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