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diagnosis differential symptoms dermatology hematology arthritis classification erythematosus joint management oncology pain rheumatoid sle systemic algorithm aortitis associations autoantibodies autoinflammatory
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Hypersensitivity vasculitis ... gangrenosum • IBD • RA ... • Vasculitis ... lesions • Discoid lupus
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
the Skin - Differential ... Secondary: CTD: SLE, RA ... Skin Findings: ... Disease • Cogan syndrome ... #rheumatology #
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... Disease, Rheumatoid Vasculitis ... (RA + Neutropenia ... #diagnosis #rheumatology ... #signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... inflammation Others: • Lupus ... such as systemic lupus ... purpura: strong sign ... differential #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... arteritis, Cogan's Syndrome ... ANCA associated vasculitis ... Rheumatoid Arthritis (RA ... ), Systemic lupus
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... LAC) • Sjogren Syndrome ... ribonucleoprotein) • RA ... Polymerase Ill • ANCA Vasculitis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- 10% SLE or RA ... • IgA vasculitis ... Hypersensitivity vasculitis ... • Vasculitis ... #vasculitis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
• Inflammatory Conditions ... : Rheumatologic, ... Vasculitides, IBD ... Kawasaki, Nephrotic syndrome ... ATRA, TPO, TPO-RA
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Extra-articular and Other Conditions ... Lyme disease, Vasculitis ... Scleroderma Thickened skin ... Extrarticular #conditions ... differential #diagnosis #rheumatology
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